Gene expression data from 4T1 irradiated tumors treated with TGFbeta blockade
Accumulating data support the concept that ionizing radiation therapy (RT) has the potential to convert the tumor into an in situ individualized vaccine; however this potential is rarely realized by RT alone. Transforming growth factor  xce xb2 (TGF xce xb2) is an immunosuppressive cytokine that is activated by RT and …