A Roadmap to the Structure-Related Metabolism Pathways of Per- and Polyfluoroalkyl Substances in Early Life Stages of Zebrafish (Danio rerio)
Our findings identified five structural categories of PFAS prone to metabolism. The metabolism pathways of PFAS are highly related to their structures and significantly impact their bioaccumulations and toxicities. We also verified CES1 as an enzyme capable of hydrolyzing diverse PFAS, with strong substrate …