Measuring microRNAs in LCM-isolated nephron segments to determine region-specific expression
To determine nephron specificity of microRNA expression that may be associated as toxicity biomarker seen in the urine, laser-capture microdissection (LCM) was performed on the 4 major segment of the nephron in control rat samples. These samples were sent to Bayer for candidate digital drop PCR measurements, NIEHS for …