Comparison of cryopreserved trout hepatocytes and liver S9 fractions as in vitro tools for bioaccumulation assessment of chemicals that undergo biotransformation in fish
The purpose of this study was to compare two in vitro systems, cryopreserved trout hepatocytes and trout liver S9 fractions, used to predict in vivo levels of biotransformation in fish.  This information is needed to refine modeled estimates of bioaccumulation for hydrophobic organic chemicals that undergo …